The mental health of children and adolescents is now on the forefront of medical providers who are seeing an increase in depression and suicide ideation. With early intervention, many are helped through cognitive behavioral therapy, together with mindfulness stress reduction, regular exercise and alternative therapies like acupuncture and yoga, hoping to avoid medication unless necessary.
Researchers at the University of Pittsburgh have completed an interesting study of young people with significant depression who are not responding to therapy and medication.
“Identifying and treating metabolic deficiencies in patients with treatment-resistant depression can improve symptoms and in some cases even lead to remission, according to new research from the University of Pittsburgh School of Medicine published online today in the American Journal of Psychiatry.
“In the published trial, the researchers looked for metabolic abnormalities in 33 adolescents and young adults with treatment-resistant depression and 16 controls. Although the specific metabolites affected differed among patients, the researchers found that 64 percent of the patients had a deficiency in neurotransmitter metabolism, compared with none of the controls.