Researchers at UC Santa Barbara have created a three-pronged approach to treating acne. This novel process includes low frequency ultrasound which pushes very tiny gold and silica particles deep into the skin, followed by the application of laser. The laser shines light onto the particles which generates heat and pushes the particles into the sebaceous glands, which deactivates them.
It is a high tech approach to a long standing problem and might prove to be life changing for those who do not want to go the way of long term antibiotics or accutane.
“Through this unique collaboration, we have essentially established the foundation of a novel therapy,” said Samir Mitragotri, professor of chemical engineering at UCSB.
(My questions: How many do you deactivate – how many are too many? Can normal sebaceous glands turn into over producing glands so that the number of overly productive glands may never decrease? What happens as you age – will those whose glands have been deactivated have leathery, dry skin when they are older?)
“According to the research, which is published in the Journal of Controlled Release, this protocol would have several benefits over conventional treatments. Called selective photothermolysis, the method does not irritate or dry the skin’s surface. In addition, it poses no risk of resistance or long-term side effects that can occur with antibiotics or other systemic treatments.”
(More questions: Do you know the effects of accumulation of gold and silica particles? If they dissolve with the laser, what tissue absorbs them?)
“It’s highly local but highly potent as well,” Mitragotri said of the treatment. “I think this would be beneficial in addressing the concerns regarding other, conventional treatments.” According to Mitragotri, this photothermolysis method is particularly suited to patients with advanced, severe or difficult-to-treat acne. The research has gone from concept to clinical trials in a relatively short amount of time. However, other more long-term elements of this therapy have yet to be studied, such as the extent of follicular damage, if any; what the most effective and beneficial parameters of this treatment may be; and what contraindications exist.“
Yes, I would like to learn more about the optimal paramenters, long lasting effects and contraindications.
I like a nutrient rich serum used with a low intensity Ultrasound and Far Infrared Light to assist with penetration into the dermal layers and heating up the tissue to keep the bacteria under control.
- Dilip Paithankar, Byeong Hee Hwang, Girish Munavalli, Arielle Kauvar, Jenifer Lloyd, Richard Blomgren, Linda Faupel, Todd Meyer, Samir Mitragotri. Ultrasonic delivery of silica–gold nanoshells for photothermolysis of sebaceous glands in humans: Nanotechnology from the bench to clinic. Journal of Controlled Release, 2015; 206: 30 DOI: 10.1016/j.jconrel.2015.03.004